How to Know If Your Bone Protocol Is Working

What to track (and when) to measure true progress


🦴 Bone Health Is a Long Game

If you’re taking supplements, changing your diet, lifting weights, and maybe even using therapies like LDN or hormone support, one question naturally comes up:

“How will I know it’s working?”

Unlike weight loss or blood pressure, you won’t see your bone density change in a week — or even in a month. Bone healing takes time, and the traditional DEXA scan doesn’t show short-term changes.

But there are ways to track progress — and they’re much more dynamic than you’ve been told.


🔬 Why Waiting for the Next DEXA Isn’t Enough

DEXA bone scans are important — but they have limitations:

  • They’re often only repeated once every 1–2 years
  • They can’t detect early shifts in bone activity
  • They don’t show why your bones are weakening

That’s why at BoneBuilder™, we use a multi-level progress system that looks at:

  • Functional markers (CTX, labs, hormones)
  • Physical function and strength
  • Patient-reported outcomes
  • Trends over time — not just snapshots

📊 The 3-Layer Progress Tracking Model

1. 🧪 Biochemical Response (First 3–6 Months)

Markers we monitor:

LabMeaning
CTX (C-terminal telopeptide)Measures bone breakdown. A drop = success.
25(OH)D, PTH, PhosphorusShow calcium economy + D balance
hs-CRP / ESRReveal inflammation that may harm bone
Hormones (E2, DHEA, T, SHBG)Show if you’re hormonally optimized

✅ A 25–50% drop in CTX in the first 3–6 months suggests your bone loss is slowing.


2. 💪 Functional Gains (1–6 Months)

We also track:

  • 🏋️ Improved strength (weighted vest tolerance, resistance lifts)
  • 🤸‍♀️ Better balance and flexibility
  • 🛏 Fewer aches, better sleep (a sign of reduced inflammation)
  • ⚖️ Muscle mass trends (via DXA body comp)
  • ✨ Energy, mood, and overall recovery

These improvements often precede BMD gains — and are just as important.


3. 🧱 Structural Progress (6–24 Months)

Finally, we look for:

  • Stabilization or increase in BMD on DEXA
  • No fragility fractures or progressive loss
  • Improved Z-score (age-adjusted bone health)
  • Long-term CTX stabilization

🧠 Note: Even a 0% BMD change can be a win if CTX has dropped and you’re stronger.


🗓️ Sample Milestone Timeline

TimepointWhat to Expect
Month 0Baseline CTX + lab panel, start protocol
Month 3Drop in CTX, improved symptoms
Month 6Full reassessment: labs + treatment plan
Month 12DEXA repeat (if indicated), tracking strength + energy
Month 18–24Move to maintenance protocol if stable

🔁 What If You’re Not Seeing Results?

We look for:

  • Missed supplement doses (compliance < 80%)
  • Inadequate D or K2 levels
  • Hidden inflammation (CRP, ESR, gut issues)
  • Hormonal blocks (low estrogen or testosterone)
  • Poor absorption or malabsorption

In some cases, we escalate to:

  • Hormone replacement (if not already on it)
  • LDN or Rapamycin for immune modulation
  • Referral for Prolia or endocrinology support

💬 FAQ: “Do I Really Have to Track All This?”

Yes and No — we do some of it for you.

Through structured check-ins, milestone labs, and optional email updates or downloadable summaries, we make sure you’re not flying blind.

You’re investing in a future without fractures — and we track every data point that gets you there.


✅ Final Thought

If you’re not measuring more than just DEXA, you’re not getting the full picture.

Real bone progress shows up:

  • In labs like CTX
  • In your strength and balance

In how your body feels and functions